Resuscitation Drugs
Quick Reference Guide

 

 Reviewed by Carl Kuschel and Victoria Wells (CNE)
December 2007
Clinical Guidelines Back Newborn Services Home Page

Drugs for Resuscitation - Quick Reference Guide

Medication

Adrenaline

Naloxone

Sodium Bicarbonate

Calcium Gluconate
Concentration 1:10,000 0.4mg/ml 8.4% 10%
Dose 0.1ml/kg 0.3ml/kg 0.1mg/kg 2mmol/kg 0.5ml/kg
Route IV ETT IM/IV IV IV
Weight (g)  
500 0.05ml 0.15ml 0.13ml 1.0ml 0.25ml
750 0.08ml 0.23ml 0.19ml 1.5ml 0.38ml
1000 0.10ml 0.30ml 0.25ml 2.0ml 0.50ml
1250 0.13ml 0.38ml 0.31ml 2.5ml 0.63ml
1500 0.15ml 0.45ml 0.38ml 3.0ml 0.75ml
1750 0.18ml 0.53ml 0.44ml 3.5ml 0.88ml
2000 0.20ml 0.60ml 0.50ml 4.0ml 1.00ml
2500 0.25ml 0.75ml 0.63ml 5.0ml 1.25ml
3000 0.30ml 0.90ml 0.75ml 6.0ml 1.50ml
3500 0.35ml 1.05ml 0.88ml 7.0ml 1.75ml
4000 0.40ml 1.20ml 1.0ml 8.0ml 2.00ml
4500 0.45ml 1.35ml 1.0ml 9.0ml 2.25ml
5000 0.50ml 1.50ml 1.0ml 10.0ml 2.50ml
Notes: 1. Appropriate dose must be charted on Drug Prescription Chart.  Please chart the concentration of the medication, as well as the volume.
2. Choose the weight most appropriate for the baby (above).
3. Dosage range for adrenaline 1:10,000  0.1-0.3ml/kg.
May be diluted to 1-2ml with saline.
4. Naloxone may be given via ETT if necessary.
5. Dosage range for bicarbonate 1-2mmol/kg.
Give slowly over at least 2 minutes (preferably longer)
6. Calcium is not a routine resuscitation drug.  It is used for the treatment of symptomatic hyperkalaemia or hypocalcaemia.
Dosage range for calcium is 0.5-2.0ml/kg.
Give slowly over 30 minutes.
Observe for bradycardia.